who to donate to

I watched Stand Up To Cancer last night and found myself crying at the hope they give. I wasn’t feeling hopeful for me, but began to think they may find better treatment for my type of cancer before the next family member gets it too.
Then I started thinking about all the different organizations that ask for our money in the hope (there’s that word again) of being able to find a cure for all of the different cancers. If you donate, how do your make the choice of who gets your money? I raised money for CIBC Run For The Cure because it was in Canada and targeted breast cancer. Stand Up To Cancer is Canada and the U.S.
Which, of all of the different agencies that ask for donations, has a better chance of finding cures? The one that targets specific cancers? The one that gets the most donation dollars? The one that uses the least of the donations for admin costs?
All of them have their good points and they’ve found out some truly life-saving stuff over the years but I wish all the donation money went into one big cancer pot with one big plan. I think they’d have a better chance of finding cures or better treatments that way.